Colorado has a reputation for indulging in beer and marijuana. And according to federal data, it's an earned distinction.
— Christopher Ingraham (@_cingraham) May 23, 2016
Unfortunately, as Keith Humpreys, a professor of psychiatry at Stanford, points out in the Washington Post, Colorado's residents use cocaine and opioids a lot too.
Colorado stands out as the only state which is a top consumer of all four substances. The state’s heavy consumption of marijuana is predictable given that the drug is legal there. The other three legalization states are heavy consumers of pot, too (Washington, Alaska and Oregon; the latter is also a leader in non-medical use of prescription opioids). But residents of the mile-high state are also heavy consumers of all non-marijuana intoxicants as well.