Denver's mayor and a 30-person delegation of state officials and business leaders will go on the inaugural flight today.
Denver International Airport
The project consists of a light rail station and a 519-room hotel, which was originally projected to cost $500 million back in 2011.
Last week, the aircraft stopped in Denver for cleaning after it carried the nurse between Cleveland and Dallas.
The new space will connect the iconic Teflon-covered Jeppesen Terminal to a new hotel and transit center.