Similar programs have popped up around the country.
It joins three other communities around Colorado using state money to offer housing, job training and mental health services to people instead of incarceration.
Some Republicans were never sold on the concept of a safe injection site. Their belief was that it would make the problem worse and enable more drug use.
District attorneys and other law enforcement officials see a spike in addiction across the state as a major source of the problem.
However, as more young people use alcohol and marijuana, they're also regarding those two substances as less dangerous.
Researchers are praising state efforts to combat the opioid epidemic, but they say more must be done to increase access to medication-assisted treatment, especially in rural areas.
Denver City Council passed a bill in November that opened the door to an injection site. Hancock's enthusiasm seemed to slow in a new interview.
The city attorney accused drug companies of “providing false and misleading information to doctors and patients about the safety of these drugs."
Denver’s move to host a supervised drug-use facility still needs approval from Colorado’s legislature before any action can be taken.
If approved through the Colorado legislature, a two-year pilot program would provide a safe place to inject illegal drugs. Trained professionals could prevent overdose deaths and the transfer of preventable diseases like hepatitis and HIV.