The stretch of I-70 from Silverthorne to Denver is particularly treacherous, with tight turns, steep climbs and sharp descents.
The charges against Aguilera-Mederos also include six counts of first-degree assault and 24 counts of attempted first-degree assault.
Records show Castellano 03 Trucking has had two trucks taken out of service for brake-related issues in the past year.
Similar to last week's deadly pileup, in August 1989 a semitrailer driver lost control on the steeply graded section of I-70 heading into Denver.
The driver of a speeding semitrailer, who appeared to one witness as "wide eyed" and "terrified" before crashing into other vehicles on a crowded Interstate 70 killing four people, made his first court appearance on Saturday after being arrested on suspicion of vehicular homicide.
Officials say four people died after a semi-truck plowed into dozens of vehicles and caused a fiery pileup on Interstate 70.
So-called urban or roof avalanches are actually more common than the kind sliding down a mountainside.
From weird test signs to weird on-ramp green light systems.
Snowstorms and wind have caused large and dangerous avalanches, some of which have covered I-70 in snow and closed the highway. And it may keep coming.
Video captured by one I-70 driver shows a cloud of snow come down the mountain and slide across the interstate.