Hundreds of scientists, including roughly 70 from Colorado, have signed a letter to President-Elect Donald Trump asking him to "...take immediate and sustained action against human-caused climate change." We ask a CU-Boulder ecologist -- is it a quixotic move? Then sisters Jessica and Robin McIntyre are dealing with the prospect of early-onset Alzheimer's. One sister has inherited the genetic mutation, the other has not. Plus, how Colorado jump started craft brewing in Italy.
![RTD Police Chief Joel Fitzgerald Sr. speaking at a press conference](https://www.cpr.org/cdn-cgi/image/width=3840,quality=75,format=auto/https://wp-cpr.s3.amazonaws.com/uploads/2022/11/221110-DENVER-SAFETY-PRESS-CONFERENCE-COLORADO-CONVENTION-CENTER-DOWNTOWN-CBD-KEVINJBEATY-31.jpg)